Abstract Search

ea0035p276 | Clinical case reports Thyroid/Others | ECE2014

Morphological and functional imaging allow better characterization of brown tumors in a patient with severe primary hyperparathyroidism

Vija Lavinia , Paun Diana , Grimon Gilles , Archambaud Frederique , Chaumet-Riffaud Philippe

Introduction: Brown tumors are rare, destructive, osteolytic bone lesions, occurring in advanced stages of hyperparathyroidism, due to increased osteoclastic activity.Case report: A 25-year-old woman presented with recent, intractable pain on the right shoulder and with hypercalcemia (Ca, 3.93 mmol/l) related to severe primary hyperparathyroidism (PTH, 494 pg/ml). Multiple osteolytic lesions, detected on the upper extremity of the right humerus, distal r...

0 shares

ea0081p34 | Calcium and Bone | ECE2022

Skeletal consequences of long-term replacement therapy with human recombinant PTH(1-34) in chronic hypoparathyroidism

Fischler Rebecca , Lecoq Anne-Lise , Briot Karine , Trabado Severine , Besson Florent , Bouziotis Jason , Goujard Cecile , Salenave Sylvie , Leboulleux Sophie , Carreira Emma , Chabrolle Christine , Bernard Corvilain , Chanson Philippe , Linglart Agnes , Grimon Gilles , Kamenicky Peter

Context: In patients with hypoparathyroidism refractory to conventional treatment, recombinant human (rh)PTH(1-84) or rhPTH(1-34) can be used as second-line therapy and effectively control hypocalcaemia. However, whether rhPTH replacement therapy is safe in the long term is unclear. Our objective was to assess bone effects of long-term therapy of chronic hypoparathyroidism with rhPTH(1-34). Methods: We conducted a monocenter retrospective cross-sectional...

0 shares

Endocrine Abstracts

Morphological and functional imaging allow better characterization of brown tumors in a patient with severe primary hyperparathyroidism

Skeletal consequences of long-term replacement therapy with human recombinant PTH(1-34) in chronic hypoparathyroidism

BiosciAbstracts